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Updated: Jan 26, 2026

Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles
Published on: December 1, 2016
[Phenotypical plasticity and targeted therapies in non-small cell lung carcinomas]
J Da Silva1, V Dalstein2, M Polette2
1Inserm UMR-S 1250 P3Cell, Pathologies Pulmonaires et Plasticité Cellulaire, Université de Reims Champagne-Ardenne, 45, rue Cognacq-Jay, 51092 Reims cedex, France.
Abstract:
Lung cancer is the most diagnosed and deathly type of cancer worldwide. It has a poor prognosis because of a late diagnosis, high metastatic potential and resistance to conventional therapies. Since the 2000s, the emergence of targeted therapies has improved patients' outcomes. However, these therapies concern only a small proportion of patients, selected by the presence of molecular biomarkers that indicate the targeting relevance. Here, we discuss the possibility that new phenotypical biomarkers could be predictive factors for targeted therapies in lung cancer.
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