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Detection and Management of Common Medication Errors in Internal Medicine Wards: Impact on Medication Costs and
Kamal Boostani1, Hamid Noshad2, Farahnoosh Farnood2
1Drug Applied Research Center, Sina Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
Abstract:
Medication errors (MEs) are a leading cause of morbidity and mortality, yet they have remained as confusing and underappreciated concept. The complex pharmacotherapy in hospitalized patients necessitates continued report and surveillance of MEs as well as persistent pharmaceutical care. This study evaluated the frequency, types, clinical significance, and costs of MEs in internal medicine wards. In this 8-month prospective and cross-sectional study, an attending clinical pharmacist visited the patients during each physician's ward round at the morning. All MEs including prescription, transcription, and administration errors were detected, recorded, and subsequently appropriate corrective interventions were proposed during these rounds. The changes in the medications' cost after implementing clinical pharmacist's interventions were compared to the calculated medications' cost, assuming that the MEs would not have been detected by clinical pharmacist and continued up to discharge time of the patients. 89% of the patients experienced at least one ME during their hospitalization. A mean of 2.6 errors per patient or 0.2 errors per ordered medication occurred in this study. More than 70% of MEs happened at the prescription stage by treating physicians. The most prevalent prescription errors were inappropriate drug selection, unauthorized drugs and untreated indication. The highest MEs occurred on cardiovascular agents followed by antibiotics, and vitamins, minerals, and electrolytes. The net effect of clinical pharmacist's contributions in medication therapy management was to decline medications' costs by 33.9%. The role of clinical pharmacy services in detection, prevention and reducing the cost of MEs is of paramount importance to internal medicine wards.
Insights
Medication errors (MEs) are frequent in hospitals, with 89% of patients experiencing them. Clinical pharmacists significantly reduced medication costs by detecting and preventing these errors.
Area of Science:
- Pharmacology
- Patient Safety
- Health Economics
Background:
- Medication errors (MEs) contribute significantly to patient morbidity and mortality.
- Complex pharmacotherapy in hospitalized patients requires ongoing surveillance and pharmaceutical care.
- MEs remain underappreciated despite their impact.
Purpose of the Study:
- To evaluate the frequency, types, clinical significance, and costs of MEs in internal medicine wards.
- To assess the impact of clinical pharmacist interventions on medication costs.
Main Methods:
- An 8-month prospective, cross-sectional study involving daily ward rounds by a clinical pharmacist.
- Prospective detection, recording, and intervention for all MEs (prescription, transcription, administration).
- Comparison of medication costs before and after pharmacist interventions.
Main Results:
- 89% of patients experienced at least one ME; an average of 2.6 errors per patient occurred.
- Over 70% of MEs originated at the prescription stage, primarily involving drug selection and untreated indications.
- MEs were most common with cardiovascular agents, antibiotics, and vitamins/minerals/electrolytes.
- Clinical pharmacist interventions led to a 33.9% reduction in medication costs.
Conclusions:
- Clinical pharmacy services are crucial for detecting, preventing, and reducing the costs associated with medication errors in internal medicine.
- Proactive pharmaceutical care can significantly mitigate the financial burden of MEs.
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