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Predictive value of a bleeding score for postpartum hemorrhage
Ada Gillissen1,2,3, Thomas van den Akker3,4, Camila Caram-Deelder1,2
1Centre for Clinical Transfusion Research Sanquin Research Leiden The Netherlands.
Research and Practice in Thrombosis and Haemostasis
|April 24, 2019
Summary
A history of postpartum hemorrhage increases risk, but a bleeding assessment tool did not reliably predict postpartum hemorrhage (PPH) in pregnant women. Further research is needed for effective PPH screening.
Area of Science:
- Obstetrics and Gynecology
- Maternal Health
- Hemorrhage Research
Background:
- Postpartum hemorrhage (PPH) poses significant clinical risks.
- Reliable screening tools are needed to identify high-risk pregnancies.
- Early identification of PPH risk is crucial for timely intervention.
Purpose of the Study:
- To evaluate the predictive value of a bleeding assessment tool for PPH exceeding 1000 mL.
- To determine if a self-administered bleeding assessment tool improves PPH prediction.
- To assess the added value of a bleeding assessment tool beyond patient history.
Main Methods:
- Prospective, two-center cohort study of 1147 pregnant women.
- Utilized a modified MCMDM-1VWD bleeding assessment tool as a self-assessment questionnaire.
- Abnormal bleeding score defined as ≥4; PPH defined as >1000 mL blood loss.
Main Results:
- 17% (197/1147) of women experienced PPH.
- Women with prior PPH had a 29% incidence of subsequent PPH.
- The bleeding assessment tool showed poor predictive ability (AUC 0.53) for PPH ≥1000 mL.
Conclusions:
- A history of PPH is a significant risk factor for recurrence.
- The studied bleeding assessment tool did not effectively discriminate women who would develop PPH.
- Current screening tools may require further refinement for accurate PPH risk prediction.
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