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Updated: Jan 26, 2026

Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells
Published on: September 1, 2019
Effect of Transcription on the white Gene Enhancer Integrated into the Intron
M M Erokhin1, A V Mikhailova1, P G Georgiev1
1Institute of Gene Biology, Russian Academy of Sciences, 119334, Moscow, Russia.
Abstract:
In this paper, we demonstrate that passing-through transcription suppresses the activity of the white gene enhancer integrated into the intron. At the same time, the SV40 transcription terminators flanking the transgene can completely remove the inhibitory effect of transcription.
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