Maxillary Giant Cell Granuloma: A Long-Term Follow-Up.

Area of Science:

• Oral and Maxillofacial Surgery
• Pathology
• Radiology

Background:

• Turner syndrome (TS) is a chromosomal condition affecting females.
• Giant cell reparative granuloma (GCRG) is a rare benign bone lesion.
• Facial pain and proptosis can indicate underlying maxillary pathology.

Observation:

• A 32-year-old female with Turner syndrome presented with chronic right-sided facial pain, sinus pressure, and right eye proptosis.
• Physical examination revealed fullness in the right infraorbital and maxillary regions.

Findings:

• Imaging (CT/MRI) identified a large, expansile, space-occupying lesion in the right maxillary sinus.
• Histological analysis confirmed the lesion as a giant cell reparative granuloma.
• Complete surgical excision was performed.

Implications:

• This case highlights a rare presentation of giant cell reparative granuloma in a patient with Turner syndrome.
• Successful surgical management resulted in a decade of disease-free follow-up.
• Understanding differential diagnoses for maxillary lesions in patients with genetic syndromes is crucial for effective treatment.