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Time for reform in transplant program-specific reporting: AST/ASTS transplant metrics taskforce
Anil Chandraker1, Kenneth A Andreoni2, Robert S Gaston3
1Transplantation Research Center, Renal Division, Brigham& Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Transplant center metrics, including survival rates, show less variation, raising questions about their usefulness. Current evaluations may hinder organ use and innovation, impacting patient choice and access to transplants.
Area of Science:
- Transplant medicine
- Health services research
- Organ transplantation outcomes
Background:
- The Scientific Registry of Transplant Recipients (SRTR) provides program-specific reports on transplant center performance.
- Metrics include waitlist mortality, organ acceptance, transplant rates, and graft/patient survival.
- Improvements in survival and decreased center variation question the clinical relevance of current metrics.
Purpose of the Study:
- To examine the utility and unintended consequences of transplant center metrics.
- To address concerns regarding the impact of current metrics on patient choice, organ utilization, and innovation.
Main Methods:
- Convening an expert taskforce by the American Society of Transplantation/American Society of Transplant Surgeons.
- Reviewing SRTR's biannual program-specific reports and center evaluation methodologies.
- Analyzing the impact of tiered ranking systems on perceived center performance.
Main Results:
- Center variation in 1-year posttransplant outcomes has decreased.
- SRTR's shift to a 5-tier ranking system exacerbates uncertainty in differentiating program performance.
- Estimates of variation between adjacent tiers are imprecise and can influence behavior.
Conclusions:
- Current transplant center metrics, primarily based on 1-year survival, offer minimal benefit for patient choice and access.
- These metrics may lead to decreased organ utilization and stifle research and innovation.
- Re-evaluation of transplant center metrics is needed to ensure clinical relevance and promote optimal transplantation practices.
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