[When is it possible to discontinue therapy in pemphigus vulgaris?]

Discontinuation of therapy in pemphigus vulgaris is risky, even after long remission under therapy. In active pemphigus vulgaris, levamisole suppresses the formation of T-cell-rosettes. The change from suppression to stimulation under the influence of levamisole, parallel to the disappearance of pemphigus antibodies seems to indicate that the therapy may be discontinued with all due caution.