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Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
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Symbiotic cardiac pacemaker.

Han Ouyang1,2, Zhuo Liu1,3, Ning Li4

  • 1CAS Center for Excellence in Nanoscience, Beijing Key Laboratory of Micro-Nano Energy and Sensor, Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, 100083, Beijing, China.

Nature Communications
|April 25, 2019
PubMed
Summary
This summary is machine-generated.

This study presents a self-powered pacemaker using a triboelectric nanogenerator to harvest energy from body motion. The implantable device successfully paces the heart and corrects arrhythmias, paving the way for future bioelectronic medicine.

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Cardiology

Background:

  • Self-powered implantable medical devices are emerging, utilizing biomechanical energy from bodily functions.
  • Cardiac pacing relies on electronic devices, often requiring battery replacements.

Purpose of the Study:

  • To demonstrate a fully implanted, self-powered pacemaker utilizing a triboelectric nanogenerator (TENG).
  • To evaluate the TENG's efficacy in energy harvesting, storage, and cardiac pacing in a large-animal model.

Main Methods:

  • Development and implantation of a symbiotic pacemaker system based on an implantable TENG.
  • Assessment of energy harvesting from cardiac motion, respiratory movement, and blood flow.
  • Evaluation of cardiac pacing effectiveness in correcting sinus arrhythmia.

Main Results:

  • The implantable TENG achieved an open circuit voltage of up to 65.2 V.
  • Energy harvested per cardiac cycle (0.495 μJ) exceeded the endocardial pacing threshold (0.377 μJ).
  • The symbiotic pacemaker successfully corrected sinus arrhythmia and prevented cardiac deterioration in a large-animal model.

Conclusions:

  • Implantable TENGs offer a viable solution for self-powered cardiac pacing, demonstrating high output performance and durability.
  • This technology represents a significant advancement in in vivo symbiotic bioelectronics for medical treatment and diagnosis.
  • The successful large-animal demonstration supports the potential of TENG-based pacemakers for clinical application.