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Updated: Jan 25, 2026

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Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation
Published on: October 2, 2015
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Publisher Correction: Glial responses to implanted electrodes in the brain
Joseph W Salatino1,2, Kip A Ludwig3, Takashi D Y Kozai4,5,6,7
1Department of Biomedical Engineering, Michigan State University, East Lansing, MI, USA.
Nature Biomedical Engineering
|April 25, 2019
Summary
This review article has been updated to correct errors in Figure 4b. The corrected figure accurately depicts glutamate signaling and purinergic P2 receptors in neurological pathways.
Area of Science:
- Neuroscience
- Molecular Biology
- Cellular Signaling
Background:
- Glutamate and purinergic signaling are critical neurotransmitter systems.
- Dysregulation of these systems is implicated in various neurological disorders.
- Accurate representation of molecular interactions is essential for understanding disease mechanisms.
Purpose of the Study:
- To correct inaccuracies in a previously published Review Article figure.
- To ensure the precise depiction of glutamate and purinergic P2 receptor interactions.
- To provide an updated and accurate resource for researchers in neuroscience.
Main Methods:
- Review of original publication figures.
- Identification of labeling and directional errors in Figure 4b.
- Correction and updating of the figure in all versions of the Review Article.
Main Results:
- The original Figure 4b contained a duplicated 'Glutamate' label.
- A crucial arrow indicating the interaction between a purinergic P2 receptor and a glutamate transporter was missing.
- The figure has been revised to accurately reflect these molecular relationships.
Conclusions:
- The corrected figure provides a more accurate representation of neurotransmitter signaling pathways.
- This ensures clarity and precision in the scientific literature.
- Updated figures are vital for advancing research in neuroscience and related fields.
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