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Associated factors for depressive disorder in patients with end-stage renal disease treated with continuous
Patrinee Traisathit1, Kasiramart Moolkham2, Narong Maneeton2
1Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand.
Insights
Depressive disorders affect 11% of continuous ambulatory peritoneal dialysis (CAPD) patients. Early end-stage renal disease (ESRD) diagnosis is linked to a higher risk of depression in these patients.
Area of Science:
- Nephrology
- Psychiatry
- Epidemiology
Background:
- Depressive disorders are a significant concern in patients undergoing continuous ambulatory peritoneal dialysis (CAPD).
- Understanding the factors associated with depression in CAPD patients is crucial for improving patient care.
Purpose of the Study:
- To determine the prevalence of depressive disorders among CAPD patients.
- To identify sociodemographic and clinical factors associated with depressive disorders in this population.
Main Methods:
- 108 stable CAPD patients were evaluated for depressive disorders.
- Multivariable logistic regression analysis was employed to identify associated factors.
- Data collected included sociodemographic information and renal condition details.
Main Results:
- 11% of CAPD patients were diagnosed with depressive disorders (minor, dysthymic, major).
- A shorter duration between end-stage renal disease (ESRD) diagnosis and initial treatment (<12 months) was significantly associated with depressive disorders (P=0.043).
- ESRD patients diagnosed within 12 months had a 3.57-fold increased risk of depression.
Conclusions:
- The prevalence of depressive disorders is high in CAPD patients.
- Early ESRD diagnosis is a key risk factor for developing depressive disorders in CAPD patients.
- Close monitoring and psychiatric consultation are recommended for high-risk CAPD patients.
Background:
The aim of this study was to primarily determine factors associated with the depressive disorders in continuous ambulatory peritoneal dialysis (CAPD).
Methods:
CAPD patients were recruited from the chronic kidney disease and CAPD Clinic of University Hospital. The stable CAPD patients for at least 3 months were included in the study. Sociodemographic data, renal conditions, and depressive disorder were evaluated. In addition to determining prevalence rate of depressive disorders, identification of factors associated with depressive disorders in CAPD patients were analyzed by using the multivariable logistic regression analysis with backward elimination procedure.
Results:
The eligible participants were 108 patients. The study found that 11% of CAPD patients were diagnosed with depressive disorders including, minor depressive, dysthymic, and major depressive disorders. Additionally, the depressive disorders were associated with the duration between the diagnosis date of the end-stage renal disease (ESRD) and the initial treatment date (P=0.043). Accordingly, the ESRD patients diagnosed in <12 months had 3.57-fold higher risk of depressive disorders than the patients diagnosed after a long time.
Conclusion:
The rate of prevalence for depressive disorder is high in the CAPD patients. Additionally, the results of this study have shown the relationship between depressive disorder and time for diagnosis of ESRD. Specifically, the risk of depressive disorder increases when patients have a shorter duration between the dates of ESRD diagnosis and initial treatment. In addition to closed monitoring for those patients, the psychiatrists should be consulted for evaluation and treatment of depressive disorders for the suspected high risk patients.
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