Related Experiment Video
Updated: Jan 25, 2026
07:51
Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
Published on: February 1, 2022
3.8K
Graphene-MoS2 with TiO2-SiO2 layers based surface plasmon resonance biosensor: Numerical development for formalin
Md Biplob Hossain1, Md Masud Rana2, Lway Faisal Abdulrazak3
1Dept. of Electrical and Electronic Engineering, Jashore University of Science and Technology, Jashore, Bangladesh.
Biochemistry and Biophysics Reports
|April 25, 2019
Summary
A novel graphene-based surface plasmon resonance (SPR) biosensor effectively detects formalin. The hybrid structure, incorporating MoS2, TiO2, and SiO2, achieves a high sensitivity of 82.83% for formalin detection.
Area of Science:
- Nanomaterials and Biosensing
- Surface Plasmon Resonance (SPR) Spectroscopy
- Chemical Sensing Technologies
Background:
- Formalin (formaldehyde) detection is crucial in various industries, including food safety and medical diagnostics.
- Existing biosensing methods often face limitations in sensitivity and specificity.
- Hybrid nanomaterials offer enhanced properties for advanced biosensor development.
Purpose of the Study:
- To numerically develop and investigate a novel SPR biosensor for formalin detection.
- To evaluate the sensitivity enhancement of a hybrid Graphene-MoS2-TiO2-SiO2 structure.
- To compare the performance of the proposed sensor with conventional and simpler hybrid structures.
Main Methods:
- Development of a surface plasmon resonance (SPR) biosensor using the attenuated total reflection (ATR) method.
- Angular interrogation technique to monitor changes in minimum reflectance and SPR frequency.
- Utilized Chitosan as a probe analyte for chemical reaction with formalin (target analyte).
Main Results:
- The proposed Graphene-MoS2-TiO2-SiO2 hybrid structure achieved the highest sensitivity of 82.83% for formalin detection.
- Sensitivity increased progressively with the integration of Graphene, MoS2, TiO2, and SiO2 layers.
- Simulation results accurately distinguished between the presence and absence of formalin based on SPR variations.
Conclusions:
- The developed SPR biosensor demonstrates superior sensitivity and effectiveness for formalin detection.
- The synergistic integration of Graphene, MoS2, TiO2, and SiO2 significantly enhances biosensor performance.
- This hybrid structure holds promise for sensitive and reliable formalin monitoring applications.
Related Concept Videos
01:24Numerical Calculations
1.2K
In engineering applications, the representation of the numerical value is critical. Presenting or reporting the answer is one of the essential parts of engineering practices. Numerical calculations are performed using handheld calculators or computers since numerically accurate answers are always preferred.
The solution to a problem is obtained using different methods. While manually solving algebraic symbols is one of the most common methods, the graphical method is often preferred. Computers...
The solution to a problem is obtained using different methods. While manually solving algebraic symbols is one of the most common methods, the graphical method is often preferred. Computers...
1.2K
01:21Pilot and Numeric Relaying
485
Pilot relaying is a type of differential protection used in power systems. It compares electrical quantities at the terminals of equipment via a communication channel instead of direct relay interconnection. This method is essential for transmission lines where the terminals are far apart, typically up to 80 km for lines with 69 to 115 kV ratings. Four types of communication channels are used for pilot relaying:
485
02:52Resonance
64.9K
The Lewis structure of a nitrite anion (NO2−) may actually be drawn in two different ways, distinguished by the locations of the N-O and N=O bonds.
64.9K
00:59How Data are Classified: Numerical Data
37.2K
Data that are countable or measurable in specific units are called numerical or quantitative data. Quantitative data are always numbers. Quantitative data are the result of counting or measuring the attributes of a population. Amount of money, pulse rate, weight, number of people living in a town, and number of students who opt for statistics are examples of quantitative data.
Quantitative data may be either discrete or continuous. All quantitative data that take on only specific numerical...
Quantitative data may be either discrete or continuous. All quantitative data that take on only specific numerical...
37.2K
01:21Layers of the Epidermis
7.9K
The epidermis, the outermost layer of the skin, is composed of several distinct layers. From deep to superficial, the layers of the epidermis are as follows:
Stratum Basale
Stratum basale, also known as the stratum germinativum, is the deepest layer of the epidermis. It is composed of a single layer of actively dividing cells called basal cells or basal keratinocytes. These cells constantly undergo cell division to replenish the upper layers of the epidermis. Additionally, melanocytes, which...
Stratum Basale
Stratum basale, also known as the stratum germinativum, is the deepest layer of the epidermis. It is composed of a single layer of actively dividing cells called basal cells or basal keratinocytes. These cells constantly undergo cell division to replenish the upper layers of the epidermis. Additionally, melanocytes, which...
7.9K
01:29Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving
303
Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
303