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Updated: Aug 10, 2026

Use of Freeze-thawed Embryos for High-efficiency Production of Genetically Modified Mice
Published on: April 2, 2020
The first genetically gene-edited babies: It's "irresponsible and too early"
Yuanwu Ma1, Lianfeng Zhang2, Chuan Qin1,3
1Key Laboratory of Human Disease Comparative Medicine National Health Commission of China (NHC) Institute of Laboratory Animal Science Peking Union Medicine College Chinese Academy of Medical Sciences Beijing China.
Abstract:
A scientist, Jiankui He of Southern University of Science and Technology of China, recently claimed at the Second International Summit on Human Genome Editing in Hong Kong on 29 November that he has created the world's first genetically altered babies using CRISPR. This announcement sparked controversy and criticism. The newly developed CRISPR/Cas9 technique has been applied to genetic modification of many kinds of animals. However, the technique is still in its infancy and many questions remain to be answered before it can be used for clinical purposes, especially for reproductive purposes.
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