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Updated: Jan 25, 2026

In Vitro Analysis of Myd88-mediated Cellular Immune Response to West Nile Virus Mutant Strain Infection
Published on: November 27, 2014
Spreading speed for a West Nile virus model with free boundary
Zhiguo Wang1, Hua Nie1, Yihong Du2
1School of Mathematics and Information Science, Shaanxi Normal University, Xi'an, 710119, Shaanxi, China.
Abstract:
The purpose of this paper is to determine the precise asymptotic spreading speed of the virus for a West Nile virus model with free boundary, introduced recently in Lin and Zhu (J Math Biol 75:1381-1409, 2017), based on a model of Lewis et al. (Bull Math Biol 68:3-23, 2006). We show that this speed is uniquely defined by a semiwave solution associated with the West Nile virus model. To find such a semiwave solution, we firstly consider a general cooperative system over the half-line [Formula: see text], and prove the existence of a monotone solution by an upper and lower solution approach; we then establish the existence and uniqueness of the desired semiwave solution by applying this method together with some other techniques including the sliding method. Our result indicates that the asymptotic spreading speed of the West Nile virus model with free boundary is strictly less than that of the corresponding model in Lewis et al. (2006).
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