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Updated: Jan 25, 2026

Contrast Enhanced Vessel Imaging using MicroCT
Published on: January 27, 2011
[Kidney function in contrast media-enhanced imaging]
M Jahn1, S Becker1, A Kribben2
1Klinik für Nephrologie, Universitätsklinikum Essen, Universität Duisburg Essen, Hufelandstr. 55, 45147, Essen, Deutschland.
Background:
The potential adverse reactions to contrast media-enhanced imaging regularly offer challenges in decision-making for nephrologists and radiologists.
Objective:
The clinical pictures of contrast media-induced acute kidney injury (CI-AKI) and nephrogenic systemic fibrosis (NSF) were evaluated, which are both caused by contrast media and closely linked to the kidney function.
Material And Methods:
The literature in PubMed and Medline was searched for the terms "kidney function" and "contrast media" and complemented by our own experiences.
Results:
While there is an ongoing re-evaluation of the clinical relevance of CI-AKI, no new cases of NSF have recently been reported under consideration of certain preventive interventions and very restricted use of gadolinium-based contrast agents.
Conclusion:
Considering the results of the latest clinical research, the potential risk of CI-AKI has been overestimated for a long time and should no longer outweigh the diagnostic benefit of contrast media-enhanced imaging. Nevertheless, the most effective prophylaxis for CI-AKI is the avoidance of unnecessary administration of contrast media.
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