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Updated: Jan 25, 2026

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions
Published on: June 30, 2021
[Progress of research on the interplay between helminth and intestinal protozoa and gut microbiota]
1National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention; Chinese Center for Tropical Diseases Research; WHO Collaborating Centre for Tropical Diseases; National Center for International Research on Tropical Diseases, Ministry of Science and Technology; Key Laboratory of Parasite and Vector Biology, National Health Commission, Shanghai 200025, China.
Abstract:
As the largest and most complex ecosystem in humans, gut microbiota resides in human or animal gastrointestinal tract with intestinal viruses and parasites. Previous studies have demonstrated that gut microbiotadysbiosis is strongly correlated with the development, progression and prognosis of multiple diseases. The parasites that are colonized in the host, may directly or indirectly affect gut microbiota and the gut microbiota-host homeostasis, and changes in the composition and diversity of gut microbiota may also affect parasitic infections and the development, progression and prognosis of parasitic diseases. This paper reviews the progress of research on the interplay between helminth and intestinal protozoa and gut microbiota.
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