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Updated: Jan 25, 2026

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An unusual endobronchial lesion: expanding the differential diagnosis
Rachel Leonard1, Charles Schultz2, Sarah Hadique1
1Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine West Virginia University Morgantown West Virginia USA.
Abstract:
Synovial sarcoma is a rare tumour, accounting for approximately 2.5-10% of all soft tissue sarcomas. In the thorax, it most often presents as a large, homogenous mass and, most commonly, is the result of extrathoracic tumour metastasis. Here, we report a case of a 73-year-old male who presented to the hospital after a motor vehicle collision. Chest computed tomography demonstrated a 2.0 × 2.4 cm left lower lobe pulmonary nodule with endobronchial extension and a 2.5 × 2.1 cm right-sided kidney mass. He was eventually diagnosed with monophasic synovial sarcoma. To date, only seven other cases of primary pulmonary synovial sarcoma with endobronchial extension have been reported. A review of the cases and literature is discussed.
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