Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple endocrine adenomatosis syndromes.

R N Schimke

    Advances in Internal Medicine
    |January 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Multiple Endocrine Neoplasia (MEN) syndromes I and II are distinct, hereditary tumor conditions. Studying these rare genetic disorders offers insights into endocrine embryology and neoplasia, aiding in early detection and treatment.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    An unusual sellar mass--solitary plasmacytoma.

    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2004
    Same author

    Extragonadal germ cell tumors in brothers.

    American journal of medical genetics·1999
    Same author

    Two distinct phenotypes caused by two different missense mutations in the same codon of the VHL gene.

    American journal of medical genetics·1999
    Same author

    Functioning carotid paraganglioma in the von Hippel-Lindau syndrome.

    American journal of medical genetics·1999
    Same author

    Genetic and biochemical normalization in female carriers of Duchenne muscular dystrophy: evidence for failure of dystrophin production in dystrophin-competent myonuclei.

    Neurology·1995
    Same author

    Detection of new paternal dystrophin gene mutations in isolated cases of dystrophinopathy in females.

    American journal of human genetics·1994

    Area of Science:

    • Endocrinology
    • Genetics
    • Oncology

    Background:

    • Multiple Endocrine Neoplasia (MEN) types I and II are distinct genetic tumor syndromes with autosomal dominant inheritance.
    • Overlap between MEN I and II is minimal, explained by secondary endocrine effects or shared neuroectodermal differentiation defects.

    Purpose of the Study:

    • To highlight the significance of studying MEN syndromes despite their rarity.
    • To underscore the value of MEN research in understanding endocrine embryology and neoplasia.

    Main Methods:

    • Review of existing literature on MEN I and II.
    • Analysis of genetic and clinical features of MEN syndromes.
    • Discussion of diagnostic and therapeutic implications.

    Main Results:

    Related Experiment Videos

    • MEN syndromes are hereditary, allowing for early detection and treatment.
    • Hormone radioimmunoassay aids in diagnosing asymptomatic individuals.
    • Study of MEN syndromes provides crucial insights into endocrine system embryogenesis.

    Conclusions:

    • MEN syndromes serve as valuable models for understanding endocrine neoplasia.
    • Research into MEN may lead to novel therapies for hormone-producing tumors.
    • Early detection and treatment strategies are critical for hereditary endocrine tumor conditions.