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Predictors of successful endovascular treatment in severe cerebral venous sinus thrombosis

Xiaoxu Yang1, Fang Wu1, Yuehong Liu1

  • 1Department of Radiology Xuanwu Hospital Beijing China.

Annals of Clinical and Translational Neurology
|April 26, 2019
PubMed

Insights

Acute clot sign on MRBTI predicts successful recanalization in severe cerebral venous sinus thrombosis (CVT) patients undergoing endovascular therapy. This imaging technique aids in selecting appropriate CVT patients for treatment.

Area of Science:

  • Neurology
  • Radiology
  • Interventional Radiology

Background:

  • Cerebral venous sinus thrombosis (CVT) is a serious condition requiring effective treatment.
  • Identifying patients likely to benefit from endovascular therapy is crucial for optimizing outcomes.

Purpose of the Study:

  • To evaluate thrombus characteristics that predict recanalization extent in severe CVT.
  • To identify patients most likely to benefit from endovascular therapy.

Main Methods:

  • Prospective study of severe CVT patients undergoing endovascular treatment.
  • Magnetic resonance black-blood thrombus imaging (MRBTI) assessed clot signal-to-noise ratio, age, and volume.
  • Digital subtraction angiography (DSA) evaluated recanalization post-treatment.

Main Results:

  • Acute clot sign (ACS) on MRBTI was significantly associated with complete recanalization (P < 0.001).
  • No significant difference in baseline clot volume between complete and partial recanalization groups.
  • MRBTI identified ACS in 39 and subacute clot sign (SCS) in 71 of 110 thrombosed segments.

Conclusions:

  • ACS on MRBTI can predict complete recanalization in CVT patients undergoing endovascular therapy.
  • MRBTI is a valuable tool for assessing clot composition and guiding treatment selection for CVT.
Abstract

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