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Updated: Jan 25, 2026

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
Published on: February 2, 2024
Development of a periprosthetic joint infection by Abiotrophia defectiva years after total knee arthroplasty
Trevor R Tooley1, Matthew P Siljander2, Michael Hubers2
1Oakland University William Beaumont School of Medicine, Rochester Hills, MI, USA.
Abstract:
A 74-year-old male presented with acute right knee pain and inability to ambulate. The patient had a total knee arthroplasty, previously complicated by a periprosthetic femur fracture requiring surgical fixation and subsequent methicillin-resistant Staphylococcus epidermidis periprosthetic joint infection treated via two-stage revision. Cultures from knee fluid aspiration were positive for Abiotrophia defectiva. Identification was confirmed using matrix-assisted laser desorption ionization-time of flight mass spectrometry. The patient underwent a two-stage revision. Between stages, the patient received intravenous ceftriaxone for six weeks with subsequent normalization of inflammatory markers. Diagnosis of periprosthetic joint infection with identification of the organism is important to guide appropriate treatment.
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