Related Experiment Video
Updated: Jan 25, 2026

Self-reporting Scaffolds for 3-Dimensional Cell Culture
Published on: November 7, 2013
Figure of 3-sign: a case report
Agata Wiktoria Henzel1, Markus Schwerzmann1
1Department of Cardiology, Center for Congenital Heart Disease, University Hospital Inselspital, University of Bern, Freiburgstrasse 15, 3010 Bern, Switzerland.
Background:
A 50-year-old mother of four children was newly diagnosed with arterial hypertension and bilateral neck pulsations.
Case Summary:
Her current blood pressure was 170/100 mmHg in the right arm and 122 mmHg systolic in the right ankle. There was a radio-femoral delay palpable. The electrocardiogram showed signs of left ventricular hypertrophy. On the chest X-ray, a figure of 3-sign was found at the aortic knuckle and notching of the inferior ribs was present. An echocardiogram showed concentric left ventricular hypertrophy, a mildly stenotic bicuspid aortic valve, and a low peak-gradient across the descending aorta. Magnetic resonance imaging demonstrated severe focal coarctation with complete interruption of the descending aorta. Large collaterals vessels were present, effectively bridging the aortic interruption.
Discussion:
In light of the extensive collateral vessels and the bleeding risk, an extra-anatomic aortic bypass was considered the least risky procedure. The patient agreed to the intervention and had an uncomplicated surgical course and recovery. At the 12-month follow-up, she was doing well and normotensive on Lisinopril 5 mg OD.
More Related Videos
05:39Generating Strictly Controlled Stimuli for Figure Recognition Experiments
Published on: March 18, 2019
07:19Identifying Targets of Human microRNAs with the LightSwitch Luciferase Assay System using 3'UTR-reporter Constructs and a microRNA Mimic in Adherent Cells
Published on: September 28, 2011
Related Concept Videos
Uncertainty in Measurement: Significant Figures
Rules for Significant Figures
It should be emphasized that when we represent measured values, the...
Significant Figures in Calculations
Signs of Puberty
Introduction to the Sign Test
Sign Convention
The normal force acts perpendicular to the beam's cross-section and can...