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Prevalence and Risk Factors of Hypovitaminosis-D in Children with Cognitive and Movement Disorders
Anu Susan George1, M C Mathew2, Anna Mathew3
1MOSC Medical College, Kolenchery, Kerala, India.
Insights
Vitamin D deficiency is highly prevalent in children with neurodevelopmental disabilities, affecting over 72%. Risk factors were more common in deficient children, highlighting a significant public health concern.
Area of Science:
- Pediatric Endocrinology
- Neurodevelopmental Disorders
- Nutritional Science
Background:
- Vitamin D deficiency (hypovitaminosis-D) is a growing concern globally.
- Children with neurodevelopmental disabilities may have unique risk factors for vitamin D deficiency.
- Understanding prevalence and risk factors is crucial for targeted interventions.
Purpose of the Study:
- To determine the prevalence of hypovitaminosis-D in children with intellectual and movement disorders.
- To identify potential risk factors associated with vitamin D deficiency in this population.
Main Methods:
- A cross-sectional study was conducted on 90 children diagnosed with neurodevelopmental disabilities.
- Data collected included serum vitamin D levels, sun exposure, mobility, diet, skin color, and anti-epileptic medication use.
- Children were categorized into cognitive and movement disability groups.
Main Results:
- A high prevalence of vitamin D deficiency (72.2%) was observed in the study cohort.
- Cognitive disability group showed 76.1% deficiency, while the movement disability group had 68.2%.
- 86% of children exhibited at least one sign of vitamin D deficiency; risk factors were more prevalent in deficient children.
Conclusions:
- Vitamin D deficiency is widespread among children with neurodevelopmental disabilities.
- The identified risk factors appear more common in vitamin D deficient children within this group.
- Further research and clinical attention are warranted to address vitamin D status in these vulnerable children.
Objectives:
To document the prevalence of hypovitaminosis-D in children with intellectual and movement disorders and to identify the risk factors in vitamin D deficient children.
Methods:
This is a cross-sectional study on 90 children with neurodevelopmental disabilities. The prevalence of hypovitaminosis-D and the risk factors such as sun exposure, age-appropriate mobility, diet, skin color and anti-epileptic medications were examined in children with cognitive disorders and movement disorders.
Results:
The mean serum vitamin D level in children with cognitive disability (n = 46) was found to be 26.7 ± 16.3 ng/L and in the children with movement disability (n = 44) it was 27.9 ± 10.5 ng/L. Though the risk factors were found in greater numbers in children in the deficient group (vitamin D < 30 ng/L), the difference between the two groups was not significant. Of the 90 children, 86 (95.5%) had at least one sign of vitamin D deficiency. Lowest levels of vitamin D were seen in autistic spectrum disorder and learning disabilities in the Cognitive Disability group and hemiplegia in the Movement Disability group.
Conclusions:
The prevalence of vitamin D deficiency in children with neurodevelopmental disabilities was 72.2%, with 76.1% in the cognitive disability group and 68.2% in the movement disability group. The risk factors were more common in vitamin D deficient children.
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