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Related Concept Videos

Synthesis and Decomposition Reactions02:17

Synthesis and Decomposition Reactions

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Synthesis and decomposition are two types of redox reactions. Synthesis means to make something, whereas decomposition means to break something. The reactions are accompanied by chemical and energy changes. 
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Amino acids03:42

Amino acids

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Amino acids are the monomers that comprise proteins. Each amino acid has the same fundamental structure, which consists of a central carbon atom, or the alpha (α) carbon, bonded to an amino group (NH2), a carboxyl group (COOH), and to a hydrogen atom. Every amino acid also has another atom or group of atoms bonded to the central atom known as the R group. There are 20 common amino acids present in proteins, each with a different R group. Variation in the amino acid sequence is responsible for...
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Transfer RNA Synthesis02:36

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One of the unique features of tRNA is the presence of modified bases. In some tRNAs, modified bases account for nearly 20% of the total bases in the molecule. Altogether, these unusual bases protect the tRNA from enzymatic degradation by RNases.
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Dehydration Synthesis01:15

Dehydration Synthesis

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Overview
Dehydration synthesis (also called a condensation reaction) is the chemical process in which two molecules covalently link together to form a new molecule, along with the release of a water molecule. Many physiologically important compounds form by dehydration synthesis reactions, such as complex carbohydrates, proteins, DNA, and RNA.
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Lagging Strand Synthesis01:59

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During replication, the complementary strands in double-stranded DNA are synthesized at different rates. Replication first begins on the leading strand. Replication starts later, occurs more slowly, and proceeds discontinuously on the lagging strand.
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Mixtures of Acids03:27

Mixtures of Acids

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The pH of a solution containing an acid can be determined using its acid dissociation constant and its initial concentration. If a solution contains two different acids, then its pH can be determined using one of several methods depending upon the relative strength of the acids and their dissociation constants.
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Related Experiment Video

Updated: Jan 25, 2026

Synthesis of Cd-free InP/ZnS Quantum Dots Suitable for Biomedical Applications
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Polylactic acid: synthesis and biomedical applications.

M S Singhvi1, S S Zinjarde1, D V Gokhale2

  • 1Institute of Bioinformatics and Biotechnology, Savitribai Phule Pune University, Pune, India.

Journal of Applied Microbiology
|April 26, 2019
PubMed
Summary

Polylactic acid (PLA) is a versatile biopolymer derived from renewable resources, ideal for biomedical uses due to its biocompatibility. Blending PLA enhances its properties, expanding applications in drug delivery, implants, and tissue engineering.

Keywords:
biocompatiblebiodegradabledrug deliveryimplantsl- and d-lactic acidpolylactic acid

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Area of Science:

  • Polymer Science
  • Biomaterials Engineering
  • Biomedical Engineering

Background:

  • Polylactic acid (PLA) is a promising biopolymer derived from renewable resources like corn and sugarcane.
  • Its biocompatibility, biodegradability, and mechanical strength make it suitable for biomedical applications.
  • Limitations include slow degradation, hydrophobicity, and low impact toughness, often addressed by blending.

Purpose of the Study:

  • To review the production, synthesis, and biomedical applications of Polylactic acid (PLA).
  • To discuss the relationship between PLA material properties, manufacturing processes, and product development.
  • To explore how blending PLA with other polymers can overcome limitations and create novel materials.

Main Methods:

  • Literature review of Polylactic acid (PLA) production and synthesis.
  • Analysis of PLA properties, including biocompatibility, biodegradability, and mechanical strength.
  • Examination of various PLA blends and their applications in drug delivery, implants, sutures, and tissue engineering.

Main Results:

  • Polylactic acid (PLA) is eco-friendly and suitable for internal use due to its non-toxic nature.
  • Blending Polylactic acid (PLA) with other polymers effectively improves its properties and expands its applications.
  • PLA and its copolymers show significant promise in tissue engineering for tissue restoration.

Conclusions:

  • Polylactic acid (PLA) is a versatile biomaterial with broad biomedical potential.
  • Material properties, manufacturing processes, and blending strategies are key to developing advanced PLA-based products.
  • Further research into PLA blends will continue to drive innovation in medical devices and regenerative medicine.