Related Experiment Video
Updated: Jan 25, 2026

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats
Published on: March 7, 2025
Comparative study of endolaser versus cryocoagulation in vitrectomy for rhegmatogenous retinal detachment
Maico Bentivoglio1, Christophe Valmaggia1, Hendrik P N Scholl2,3,4
1Eye Clinic, Cantonal Hospital Sankt Gallen, Rorschacherstrasse 95, CH-9007, Sankt Gallen, Switzerland.
Background:
To investigate the influence of different types of retinopexy on the outcome of rhegmatogenous retinal detachment (RRD) repair.
Method:
All patients with RRD who underwent pars plana vitrectomy (PPV) between January 2013 and December 2017 were included. Analysed surgical factors were types of retinopexy (cryocoagulation, endolaser, combined). Subgroup analysis was performed in patients with primary proliferative vitreoretinopathy (PVR), and/or the necessity of a primary silicone oil fill.
Results:
A total of 1017 eyes with retinal detachment were included. The predominant type of retinopexy used during PPV was cryocoagulation in 492 eyes, followed by a combined cryocogulation/endolaser in 306 eyes and laserretinopexy in only 219 eyes. Overall, the re-detachment rate was 10.1%. In most of the cases (53.6%) the main reason for re-detachment was insufficient retinopexy, followed by a PVR-reaction in 37.3%, and new site break in 9.1%. No significant difference in the rate of re-detachment was found between the different types of retinopexy (p = 0.309). However, subgroup analysis showed a significantly higher rate of re-detachment in patients with a primary PVR (p = 0.0003), and in the group with silicone oil as the primary tamponade (p = 0.0001).
Conclusion:
The data suggests that the type of retinopexy has little relevance for the surgical outcome of PPV for the primary RRD. However, patients with primary PVR and primary silicone oil fills were at a significantly increased risk for re-detachment.
Related Concept Videos
Comparing Copy Number Variations and SNPs
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...
Comparing the Survival Analysis of Two or More Groups
Comparing Experimental Results: Student's t-Test
Comparative Excretory Systems
Comparing Mitochondrial, Chloroplast, and Prokaryotic Genomes
Comparing Intermolecular Forces: Melting Point, Boiling Point, and Miscibility
Temporary attractive forces like dispersion are present in all molecules, whether they are polar or nonpolar. They...

