Meningococcal infections in the German Democratic Republic 1971-1984

Area of Science:

• Microbiology
• Epidemiology
• Infectious Diseases

Background:

• Since 1979, microbiological investigations of meningococcal strains in the German Democratic Republic (GDR) have been conducted.
• A notable increase in meningococcal infections has been observed despite a generally low incidence.

Purpose of the Study:

• To investigate correlations between epidemiological and microbiological data of meningococcal isolates.
• To analyze the age distribution, clinical presentation, and regional occurrence of meningococcal strains.

Main Methods:

• Microbiological investigation of meningococcal strains isolated in the GDR from May 1979 to 1984.
• Serogrouping of 515 out of 650 isolated strains.
• Recording of epidemiological data including age distribution, clinical picture, and regional distribution.

Main Results:

• Serogroup B was the most common (292 strains), followed by serogroup C (125 strains) and serogroup A (54 strains).
• Other serogroups identified included X, Y, Z, W-135, and 29E.
• No substantial changes in the distribution of serogroups were observed during the study period.
• Rifampicin chemoprophylaxis for contacts was implemented in 1981.

Conclusions:

• The study provides insights into the microbiological and epidemiological characteristics of meningococcal infections in the GDR.
• Understanding these patterns is crucial for public health interventions and disease control strategies.
• The introduction of chemoprophylaxis marks an effort to manage the increasing incidence.