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Meningococcal infections in the German Democratic Republic 1971-1984
Abstract:
Since May 1979 all meningococcal strains isolated in the GDR have been investigated microbiologically. Despite a generally low incidence, a marked increase in meningococcal infections has been observed. From a total of 650 strains sent to our institute up to 1984, 515 could be serogrouped. 54 strains belonged to serogroup A, 292 to B, 125 to C, two to X, eight to Y, one to Z, 30 to W-135 and three to 29E. There were no substantial changes in the distribution of the groups. In our study we tried to find out whether there are any correlations between the epidemiological and microbiological data. A record was made of the age distribution, clinical picture and regional distribution of the meningococcal strains isolated. Rifampicin chemoprophylaxis of contacts was introduced in 1981.
Insights
A marked increase in meningococcal infections was observed in the GDR, with serogroup B strains being the most prevalent. This study analyzed epidemiological and microbiological data of meningococcal isolates.
Area of Science:
- Microbiology
- Epidemiology
- Infectious Diseases
Background:
- Since 1979, microbiological investigations of meningococcal strains in the German Democratic Republic (GDR) have been conducted.
- A notable increase in meningococcal infections has been observed despite a generally low incidence.
Purpose of the Study:
- To investigate correlations between epidemiological and microbiological data of meningococcal isolates.
- To analyze the age distribution, clinical presentation, and regional occurrence of meningococcal strains.
Main Methods:
- Microbiological investigation of meningococcal strains isolated in the GDR from May 1979 to 1984.
- Serogrouping of 515 out of 650 isolated strains.
- Recording of epidemiological data including age distribution, clinical picture, and regional distribution.
Main Results:
- Serogroup B was the most common (292 strains), followed by serogroup C (125 strains) and serogroup A (54 strains).
- Other serogroups identified included X, Y, Z, W-135, and 29E.
- No substantial changes in the distribution of serogroups were observed during the study period.
- Rifampicin chemoprophylaxis for contacts was implemented in 1981.
Conclusions:
- The study provides insights into the microbiological and epidemiological characteristics of meningococcal infections in the GDR.
- Understanding these patterns is crucial for public health interventions and disease control strategies.
- The introduction of chemoprophylaxis marks an effort to manage the increasing incidence.