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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Chronic kidney disease in cats attending primary care practice in the UK: a VetCompassTM study
Megan Conroy1, David C Brodbelt1, Dan O'Neill1
1Department of Veterinary Clinical Sciences, Royal Veterinary College-Hawkshead Campus, Hatfield, UK.
Insights
Chronic kidney disease (CKD) affects 1.2% of UK cats. Early diagnosis and management, including renal diets, improve survival times for feline CKD patients.
Area of Science:
- Veterinary Medicine
- Epidemiology
- Animal Health
Background:
- Chronic kidney disease (CKD) is a prevalent condition in feline populations.
- It is a leading cause of mortality in cats over five years old.
- Limited research exists on feline CKD within UK primary care settings.
Purpose of the Study:
- To estimate the prevalence of CKD in cats in UK primary care practices.
- To identify risk factors associated with CKD diagnosis.
- To investigate survival rates for cats diagnosed with CKD.
Main Methods:
- A nested case-control and cohort study design was employed.
- Data were collected from 353,448 cats attending 244 UK primary care veterinary practices between January 1, 2012, and December 31, 2013.
- Prevalence, diagnostic investigations, management, and survival times were analyzed.
Main Results:
- The prevalence of CKD was estimated at 1.2% (95% CI 1.1–1.3%).
- Most CKD cats (66.6%) presented with clinical signs.
- Diagnostic monitoring (serum creatinine, urine protein:creatinine ratio, blood pressure) and use of renal diets were variable.
- Median survival time post-diagnosis was 388 days.
Conclusions:
- This study provides generalizable evidence on feline CKD prevalence and outcomes in UK primary care.
- Findings can assist veterinarians in improving the diagnosis and management of feline CKD.
- Enhanced understanding can improve the health and welfare of cats with CKD.
Abstract:
Chronic kidney disease (CKD) is a frequent diagnosis in cats attending primary care practice and the most frequent cause of death in cats aged over five years, yet there is limited published research for CKD in cats attending primary care practice. This study aimed to estimate the prevalence of CKD and investigate risk factors for diagnosis and survival of cats diagnosed with CKD in UK primary care practices. The study included cats attending VetCompassTM practices from January 1, 2012 to December 31, 2013. A nested case-control and cohort study were undertaken. From 353,448 cats attending 244 clinics, the prevalence of CKD was estimated as 1.2 per cent (95 per cent CI 1.1 per cent to 1.3 per cent). Most cats with CKD had clinical signs at diagnosis (66.6 per cent). Few cats underwent investigations or monitoring of serum creatinine (32.6 per cent), urine protein:creatinine ratio (14.9 per cent) or blood pressure measurement (25.6 per cent). A proprietary renal diet was the most frequently prescribed management (63.8 per cent). Median survival time following diagnosis was 388 days (IQR 88-1042 days). This study provides generalisable evidence from the wider cat population to aid veterinarians in improved diagnosis and management of CKD that can benefit the health and welfare of cats with CKD in the UK.
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