Related Experiment Video
Updated: Jan 25, 2026
07:44
In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
3.4K
Ocular biometry and refractive outcomes using two swept-source optical coherence tomography-based biometers with
Miki Kamikawatoko Omoto1, Hidemasa Torii1, Sachiko Masui1
1Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Scientific Reports
|April 27, 2019
Summary
This study found that while ocular biometry measurements differ between the ARGOS and IOLMaster 700 swept-source devices, both provide clinically acceptable intraocular lens power calculations for cataract surgery patients.
Area of Science:
- Ophthalmology
- Biomedical Engineering
- Optical Coherence Tomography
Background:
- Accurate ocular biometry is crucial for effective intraocular lens (IOL) power calculation in cataract surgery.
- Different swept-source optical coherence biometers utilize varying refractive index methodologies, potentially impacting measurement consistency.
Purpose of the Study:
- To compare ocular biometry measurements and refractive outcomes between the ARGOS and IOLMaster 700 swept-source optical coherence biometers.
- To evaluate the accuracy of IOL power calculations using standard formulas with data from both devices.
Main Methods:
- A comparative study involving 106 eyes of 106 cataract patients.
- Measurement of axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), and mean anterior corneal radius of curvature (Rm) using ARGOS and IOLMaster 700.
- Analysis of postoperative refractive outcomes using Barrett Universal II, Haigis, Hoffer Q, and SRK/T formulas.
Main Results:
- Significant differences were observed in mean AL, CCT, ACD, and Rm between the ARGOS and IOLMaster 700 (P < 0.001).
- Mean lens thickness (LT) showed no significant difference between the two biometers.
- The percentages of eyes within ±0.50 and ±1.00 diopters of predicted refraction were not significantly different (P > 0.05).
Conclusions:
- Both ARGOS and IOLMaster 700 biometers yield clinically acceptable accuracy for IOL power calculation.
- Despite measurement variations in ocular biometry parameters, refractive outcomes remain comparable between the two swept-source devices.
Related Concept Videos
01:26Influence of Earth's Curvature and Atmospheric Refraction on Leveling
916
During leveling, the Earth's curvature and atmospheric refraction introduce deviations in the line of sight from a true horizontal reference. When the line of sight is leveled, it remains perpendicular to the plumb line only at a single point. Beyond this, it deviates due to the Earth’s curvature, represented by the correction C. For a sight distance D, the deviation can be derived using the relationship:This relationship shows that the deviation increases quadratically with distance. Over a...
916
02:39Indicators
59.9K
Certain organic substances change color in dilute solution when the hydronium ion concentration reaches a particular value. For example, phenolphthalein is a colorless substance in any aqueous solution with a hydronium ion concentration greater than 5.0 × 10−9 M (pH < 8.3). In more basic solutions where the hydronium ion concentration is less than 5.0 × 10−9 M (pH > 8.3), it is red or pink. Substances such as phenolphthalein, which can be used to determine the pH of a solution, are...
59.9K
01:18Cardiovascular Drugs: Classification based on Therapeutic Indications
4.1K
Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However,...
4.1K
01:26Pharmaceutical Equivalents
192
As defined by regulatory standards, pharmaceutical equivalents require generic drug products to have identical dosage forms and chemically identical active pharmaceutical ingredients (APIs). They must adhere to compendial or applicable standards for potency, content uniformity, disintegration times, and dissolution rates. In the case of modified-release dosage forms, variations in drug content are permissible as long as the delivered amount remains consistent with the innovator drug product.
192
01:19Equivalent Capacitance
2.1K
Multiple capacitors can be connected in a circuit in series or parallel configuration. When the capacitor combination is connected to a battery, the potential drop across each capacitor and the magnitude of charge stored in the individual capacitor depends on the type of the connection. The capacitor combination is replaced by a single equivalent capacitor that stores the same amount of charge as the combination for a given potential difference.
The following strategies are adopted to calculate...
The following strategies are adopted to calculate...
2.1K
01:19Equivalent Capacitance
686
From the study of resistive circuits, it is understood that employing a series-parallel combination serves as an effective strategy for simplifying circuits. Capacitors can be arranged within a circuit in one of two ways: a series configuration or a parallel configuration. The way these capacitors are connected to a battery will influence both the potential drop across each individual capacitor and the size of the charge that each capacitor can store. This is determined by the specific type of...
686