Sinonasal malignancies: Endoscopic treatment outcomes

Area of Science:

• Otolaryngology
• Neurosurgery
• Surgical Oncology

Background:

• Sinonasal malignancies are rare, heterogeneous cancers near critical neurovascular structures.
• Surgical resection is challenging due to anatomical proximity to the orbit, brain, cranial nerves, and carotid arteries.
• Open craniofacial resection has been the traditional gold standard, but carries significant morbidity.

Purpose of the Study:

• To provide an updated review of the current literature on the outcomes of endoscopic treatment for sinonasal malignancies.
• To evaluate the efficacy and safety of endoscopic endonasal approaches as an alternative to open surgery.
• To assess the impact of endoscopic approaches on survival and complication rates.

Main Methods:

• Systematic review and meta-analysis of existing case series and multi-analyses.
• Examination of evidence comparing endoscopic endonasal approaches with open craniofacial resection.
• Focus on studies reporting outcomes, survival rates, and complication profiles.

Main Results:

• Endoscopic endonasal approaches are a viable alternative for carefully selected patients with sinonasal malignancies.
• Current evidence indicates that endoscopic approaches do not compromise patient survival.
• Endoscopic techniques are associated with lower complication rates compared to open surgery.

Conclusions:

• Endoscopic endonasal surgery is a safe and effective treatment option for select sinonasal malignancies.
• This minimally invasive approach offers comparable oncologic outcomes with improved patient safety.
• Further research and standardized reporting are needed to solidify evidence-based guidelines for endoscopic sinonasal cancer treatment.