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Updated: Jan 25, 2026

Aggravation of Myocardial Ischemia upon Particulate Matter Exposure in Atherosclerosis Animal Model
Published on: December 10, 2021
Myocardial fibrosis and MitraClip: Does it even matter?
Wassim Shatila1,2, Zvonimir Krajcer1,2,3
1Department of Cardiology, Texas Heart Institute, Houston, Texas.
Abstract:
Preprocedural myocardial fibrosis as identified by magnetic resonance imaging correlates with worse outcomes after MitraClip placement. Post-MitraClip mitral regurgitation gradient >2 or ischemic cardiomyopathy also correlates with worse outcomes. In the literature, other variables are mentioned (e.g., severe tricuspid regurgitation, atrial fibrillation, postoperative mitral valve area and/or gradient) that correlate with worse post-MitraClip outcomes.
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