Related Experiment Video

Updated: Jan 25, 2026

Optimized Transfection Strategy for Expression and Electrophysiological Recording of Recombinant Voltage-Gated Ion Channels in HEK-293T Cells
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Optimized Transfection Strategy for Expression and Electrophysiological Recording of Recombinant Voltage-Gated Ion Channels in HEK-293T Cells

Published on: January 19, 2011

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Dlg1 Maintains Dendritic Cell Function by Securing Voltage-Gated K+ Channel Integrity

Xuejiao Dong1, Lisi Wei2, Xueheng Guo3,4

  • 1Ministry of Education Key Laboratory of Protein Sciences, Center for Life Sciences, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, School of Life Sciences, Beijing Key Laboratory for Immunological Research on Chronic Diseases, Institute for Immunology, Tsinghua University, Beijing 100084, China.

Journal of Immunology (Baltimore, Md. : 1950)
|April 28, 2019
PubMed
Summary

Discs large homologue 1 (Dlg1) is crucial for dendritic cell (DC) function. Loss of Dlg1 impairs DC ability to respond to antigens and support immune responses by affecting ion channels.

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