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Idiopathic inflammatory myopathies (IIM) cause significant disability, particularly in inclusion body myositis (IBM). Many patients require mobility aids and assistance with daily activities due to muscle weakness and fatigue.

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Area of Science:

  • Rheumatology
  • Neurology
  • Clinical Medicine

Background:

  • Idiopathic inflammatory myopathies (IIM) are chronic, progressive autoimmune diseases affecting muscles.
  • These conditions lead to significant physical impairment and reduced quality of life.

Purpose of the Study:

  • To assess disability levels across IIM subtypes.
  • To identify clinical symptoms linked to increased disability risk.
  • To determine the most challenging daily activities for IIM patients.

Main Methods:

  • An online survey was distributed to IIM patient support groups.
  • The survey collected data on clinical symptoms, comorbidities, and daily living limitations.
  • The Health Assessment Questionnaire (HAQ) measured disability and physical limitations.
  • Visual analogue scales (VAS) assessed symptom intensity.

Main Results:

  • High disability prevalence was noted across all IIM subtypes.
  • Inclusion body myositis (IBM) showed the highest severe to very severe disability rate (51.43%).
  • Disability correlated with muscle weakness, exercise tolerance, and fatigue.
  • 45.62% needed walking aids; 43.50% used assistive devices for hygiene.

Conclusions:

  • Patients with IIM experience substantial physical limitations.
  • Assistive devices and caregiver support can partially mitigate functional deficits.
  • Inclusion body myositis (IBM) appears to be the most disabling IIM subtype.