Related Experiment Video
Updated: Jan 25, 2026

Protocol for Culturing Sympathetic Neurons from Rat Superior Cervical Ganglia SCG
Published on: January 30, 2009
Cardiac sympathetic innervation scintigraphy with 123I-meta-iodobenzylguanidine. Basis, protocols and clinical
I Casáns-Tormo1, A Jiménez-Heffernan2, V Pubul-Núñez3
1Servicio de Medicina Nuclear, Hospital Clínico Universitario, Valencia, España; Grupo de Trabajo de Cardiología Nuclear de la Sociedad Española de Medicina Nuclear e Imagen Molecular.
Abstract:
Imaging of cardiac sympathetic innervation is only possible by nuclear cardiology techniques and its assessment is key in the evaluation of and decision-making for patients with cardiac sympathetic impairment. This review includes the basis of cardiac sympathetic scintigraphy with 123I-meta-iodobenzylguanidine (123I-MIBG), recommended protocols, patient preparation, image acquisition and quantification, reproducibility, dosimetry, etc., and also the clinical indications for cardiac patients, mainly with regard to heart failure, arrhythmia, coronary artery disease, cardiotoxicity, including its contribution to establishing the indication for and monitoring the response to implantable cardiac devices, pharmacological treatment, heart transplantation and other.
Related Concept Videos
The Sympathetic Nervous System
Sympathetic Signaling
Sympathetic preganglionic fibers release the neurotransmitter acetylcholine (ACh) onto the ganglionic neurons in the...
Sympathetic Pathways: Sympathetic Chain Ganglia
Clinical Applications of Epidermal Stem Cells
Sympathetic Activation
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET

