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The intricate hormonal interplay essential for male reproductive health begins with the release of gonadotropin-releasing hormone (GnRH) by the hypothalamus. This hormone prompts the pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). LH targets the Leydig cells in the testes, stimulating them to produce and release testosterone. In concert with testosterone, FSH acts on the Sertoli cells within the seminiferous tubules to facilitate the release of...
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Metallic solids such as crystals of copper, aluminum, and iron are formed by metal atoms. The structure of metallic crystals is often described as a uniform distribution of atomic nuclei within a “sea” of delocalized electrons. The atoms within such a metallic solid are held together by a unique force known as metallic bonding that gives rise to many useful and varied bulk properties.
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Solids in which the atoms, ions, or molecules are arranged in a definite repeating pattern are known as crystalline solids. Metals and ionic compounds typically form ordered, crystalline solids. A crystalline solid has a precise melting temperature because each atom or molecule of the same type is held in place with the same forces or energy. Amorphous solids or non-crystalline solids (or, sometimes, glasses) which lack an ordered internal structure and are randomly arranged. Substances that...
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Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
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Pancreatic Solid Pseudopapillary Tumor Associated with Elevated DHEA and Testosterone.

Elias Estifan1, Yana Cavanagh2, Ashima Kapoor1

  • 1Department of Internal Medicine, St. Joseph's University Medical Center-New York Medical College, USA.

Case Reports in Gastrointestinal Medicine
|April 30, 2019
PubMed
Summary

This case report details a rare pancreatic tumor, solid pseudopapillary neoplasm (SPN), presenting with elevated dehydroepiandrosterone (DHEA) and testosterone. This hormonal imbalance resolved after surgical removal of the pancreatic SPN.

Area of Science:

  • Endocrinology
  • Oncology
  • Gastroenterology

Background:

  • Solid pseudopapillary neoplasms (SPN) are rare pancreatic tumors with low malignant potential, typically presenting asymptomatically or with mass effect.

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  • SPNs are usually endocrinologically inactive, showing no significant elevation in common tumor markers or pancreatic/liver function tests.