Related Experiment Video
Updated: Jan 25, 2026
07:44
Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
6.7K
Unusual Case of Obstructive Jaundice.
Rajesh Essrani1, Eric Nellis2, Patrick Hickey2
1Internal Medicine, Lehigh Valley Health Network, Allentown, USA.
Cureus
|April 30, 2019
Summary
This study reports a rare case of obstructive jaundice caused by metastatic tonsil cancer spreading to the duodenum. It highlights an unusual pathway for head and neck cancer metastasis, emphasizing the need for broader diagnostic considerations.
Area of Science:
- Oncology
- Gastroenterology
Background:
- Malignant obstructive jaundice typically originates from primary periampullary tumors.
- Metastasis from head and neck cancers to the gastrointestinal tract is uncommon.
Observation:
- A 60-year-old male presented with obstructive jaundice.
- The patient was diagnosed with metastatic squamous cell carcinoma originating from the tonsil.
Findings:
- This case represents the first documented instance of tonsillar cancer metastasizing to the duodenum, causing obstructive jaundice.
- Only 12 cases of small bowel metastasis from head and neck cancers have been previously reported, mostly from laryngeal cancer.
Implications:
- This case expands the known metastatic patterns of head and neck squamous cell carcinoma.
- It underscores the importance of considering unusual metastatic sites in the differential diagnosis of obstructive jaundice.
Related Concept Videos
01:16Unusual Results
3.7K
Unusual results are those that have a very low chance of occurring. Unusual results can be identified using probabilities and the range rule of thumb. In problems involving probability, unusual results can be observed in 2 instances – an unusually high number of successes or an unusually low number of successes.
According to the range rule of thumb, any value above or below two standard deviations, 2σ from the mean, μ is considered unusual.
Maximum unusual value =...
According to the range rule of thumb, any value above or below two standard deviations, 2σ from the mean, μ is considered unusual.
Maximum unusual value =...
3.7K
01:07z Scores and Unusual Values
11.0K
The z score is one of the three measures of relative standing. It describes the location of a value in a dataset relative to the mean. z scores are obtained after the standardization of the values in a dataset. The z score for the mean is 0.
This score indicates how far a value is from the mean in terms of standard deviation. For example, if a data value has a z score of +1, the researcher can infer that the particular data value is one standard deviation above the mean. If another data...
This score indicates how far a value is from the mean in terms of standard deviation. For example, if a data value has a z score of +1, the researcher can infer that the particular data value is one standard deviation above the mean. If another data...
11.0K
01:22Chronic Obstructive Pulmonary Disease
2.4K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
2.4K
01:10Design Example: Measuring Distance Between Two Points with Obstructions
398
When measuring distances in areas with physical obstructions, such as a lake in a field, surveyors must employ techniques to calculate accurate lengths without direct line measurements. One effective method is the offset technique, which allows for precise distance estimation over inaccessible stretches.In this scenario, a surveyor must measure a side of an area that crosses a lake. Since the measuring tape cannot span the lake, the surveyor begins by establishing a baseline that aligns with...
398
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
4.3K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
4.3K
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
3.6K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
3.6K