Epigeneti-What? Approaches on Translating Research for Primary Breast Cancer Prevention

Evan K Perrault1, Grace M Hildenbrand1, Robert G Nyaga1

  • 1Brian Lamb School of Communication, Purdue University, West Lafayette, IN, United States.

Frontiers in Oncology
|April 30, 2019
PubMed

Insights

While breast cancer research receives significant funding, immediate causes remain unknown. Translating plausible environmental links into actionable advice for the public and policymakers is crucial for risk reduction.

Area of Science:

  • Environmental Health
  • Cancer Research
  • Health Communication

Background:

  • Significant financial investment in breast cancer research has not yielded conclusive immediate causes or definitive environmental links.
  • Breast cancer development is a complex, life-course process, making it challenging to establish direct causal relationships with specific exposures.
  • Existing research identifies plausible environmental links and risk reduction strategies, posing a communication challenge for public health.

Purpose of the Study:

  • To address the challenge of translating inconclusive scientific findings on environmental exposures and breast cancer into actionable public health advice.
  • To advocate for a dual approach in communicating breast cancer risk reduction strategies.
  • To analyze the strengths and weaknesses of different communication strategies for breast cancer prevention.

Main Methods:

  • Perspective analysis of current research translation strategies.
  • Evaluation of a two-pronged approach: bottom-up (public/individual focus) and top-down (policymaker focus).
  • Encouraging collaboration between scientists and health communicators.

Main Results:

  • Direct causal links between environmental exposures and breast cancer are not yet conclusive.
  • Research provides "plausible links" and risk reduction strategies for individuals.
  • A two-pronged communication approach is proposed to influence both public behavior and policy.

Conclusions:

  • Waiting for 100% conclusive scientific evidence may delay life-saving actions.
  • A combined bottom-up and top-down strategy is recommended for effective breast cancer prevention communication.
  • Interdisciplinary collaboration is essential for developing effective, theoretically-driven health communication strategies.

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