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Epigeneti-What? Approaches on Translating Research for Primary Breast Cancer Prevention
Evan K Perrault1, Grace M Hildenbrand1, Robert G Nyaga1
1Brian Lamb School of Communication, Purdue University, West Lafayette, IN, United States.
Abstract:
In fiscal year 2017, the National Cancer Institute devoted more than a half billion dollars to breast cancer research. Since 2012, the total investment has been more than $3 billion. Despite this significant investment, breast cancer still has no known immediate causes as it generally develops over the life course. Therefore, research is unable to provide the public any sort of magic bullet, or conclusive link between certain environmental exposures and the development of breast cancer later in life. What research is only able to report are likelihoods-possible links-things people might want to consider avoiding or doing in their everyday lives to reduce their future risks of developing breast cancer. This abundance of rigorously performed, albeit causally inconclusive, research focused on "plausible" links poses a challenge for health communicators who are tasked with seeking to find ways to translate this science into advice that people can act upon today. However, if society must wait for the science to provide 100% conclusive evidence before anyone ever takes action, how many lives could have been saved in the interim? Therefore, we advocate a two-pronged approach to translating scientific findings regarding environmental exposures and breast cancer prevention: a bottom-up approach-focused on informing the lay public and individuals, while simultaneously performing a top-down approach-focused on influencing policymakers. The current perspective analyzes the strengths and weaknesses to both of these approaches, and encourages scientists to work closely with health communicators to develop theoretically-driven strategies to drive positive changes over time.
Insights
While breast cancer research receives significant funding, immediate causes remain unknown. Translating plausible environmental links into actionable advice for the public and policymakers is crucial for risk reduction.
Area of Science:
- Environmental Health
- Cancer Research
- Health Communication
Background:
- Significant financial investment in breast cancer research has not yielded conclusive immediate causes or definitive environmental links.
- Breast cancer development is a complex, life-course process, making it challenging to establish direct causal relationships with specific exposures.
- Existing research identifies plausible environmental links and risk reduction strategies, posing a communication challenge for public health.
Purpose of the Study:
- To address the challenge of translating inconclusive scientific findings on environmental exposures and breast cancer into actionable public health advice.
- To advocate for a dual approach in communicating breast cancer risk reduction strategies.
- To analyze the strengths and weaknesses of different communication strategies for breast cancer prevention.
Main Methods:
- Perspective analysis of current research translation strategies.
- Evaluation of a two-pronged approach: bottom-up (public/individual focus) and top-down (policymaker focus).
- Encouraging collaboration between scientists and health communicators.
Main Results:
- Direct causal links between environmental exposures and breast cancer are not yet conclusive.
- Research provides "plausible links" and risk reduction strategies for individuals.
- A two-pronged communication approach is proposed to influence both public behavior and policy.
Conclusions:
- Waiting for 100% conclusive scientific evidence may delay life-saving actions.
- A combined bottom-up and top-down strategy is recommended for effective breast cancer prevention communication.
- Interdisciplinary collaboration is essential for developing effective, theoretically-driven health communication strategies.
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