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Updated: Jan 25, 2026
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Intradermal Inoculation of Mycobacterium avium in the Mouse Ear
Published on: July 3, 2025
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Multi-stage surgery for a multiple-level spondylodiscitis caused by multidrug-resistant Mycobacterium avium complex
Rafael García Cañas1, Francisco Javier Areta Jiménez1, Carlos Rodríguez Moro1
1Unidad de Patología Vertebral, Hospital Ruber Internacional, Madrid, Spain.
Journal of Spine Surgery (Hong Kong)
|April 30, 2019
Summary
This study details a rare case of multi-level spinal infection caused by atypical mycobacteria (Mycobacterium avium complex). Successful treatment involved complex multi-stage surgery and fusion techniques.
Area of Science:
- Spinal Surgery
- Infectious Diseases
- Mycobacterial Infections
Background:
- Atypical mycobacterial spondylodiscitis is rare, with limited reports on surgical management.
- Mycobacterium avium complex (MAC) is an opportunistic pathogen that can cause severe spinal infections.
Observation:
- A 71-year-old female presented with multi-level spondylodiscitis (L2-L3, L5-S1) due to MAC.
- The patient underwent a two-stage surgical intervention: posterior instrumentation followed by anterior debridement and fusion.
Findings:
- The patient experienced proximal junctional failure one year post-surgery, successfully managed with percutaneous fusion extension.
- The multi-stage surgical approach resulted in good pain control, satisfactory correction, and no neurological complications.
Implications:
- Multi-stage surgical treatment can be effective for complex, antibiotic-resistant atypical mycobacterial spondylodiscitis.
- Surgical management requires careful planning due to technical challenges and instrumentation level selection.
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