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Updated: Jan 25, 2026

Detecting the Water-soluble Chloride Distribution of Cement Paste in a High-precision Way
Published on: November 21, 2017
Rapid and visual detection of berberine hydrochloride based on a water-soluble pyrene derivative
Mingwei Guo1,2, Weijie Li1, Yanan Sun2
1School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Abstract:
In this study, a rapid method for the detection of berberine hydrochloride (BRH) was developed based on a water-soluble pyrenyl probe, 8-hydroxypyrene-1,3,6-trisulfonic acid (HPTS). This method features low cost, good selectivity, high sensitivity and a fast response. The sensing mechanism of this probe is attributed to the formation of a complex between HPTS and BRH induced by electrostatic interaction and π-π stacking. To the best of our knowledge, this is the first fluorescent sensor for BRH based on organic materials that has low cost and a visual response. The detection limit of this method was as low as 1.24 μM and the linear response range is 2-50 μM. This method also allowed rapid detection of BRH real samples.
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