Update on Bowman layer transplantation
Related Experiment Video
Updated: Jan 25, 2026

Micropuncture of Bowman's Space in Mice Facilitated by 2 Photon Microscopy
Published on: October 11, 2018
C Maya Tong1,2, Konine van Dijk1,3, Gerrit R J Melles1,3,4
1Netherlands Institute for Innovative Ocular Surgery (NIIOS), Rotterdam, The Netherlands.
Purpose Of Review:
Bowman layer transplantation is a novel technique that may stabilize progressive ectatic corneal changes in eyes with keratoconus, which are too steep or too thin for ultraviolet corneal crosslinking or intracorneal ring segments. In this way, patients can maintain stable vision with contact lenses, and avoid or postpone more invasive corneal transplants, such as penetrating keratoplasty or deep anterior lamellar keratoplasty. This review aims to summarize the currently available literature on Bowman layer transplantation.
Recent Findings:
Bowman layer transplantation seems to be a promising, minimally invasive procedure for managing advanced keratoconus with a reported 5-year success rate of 84%. The procedure allows patients to maintain acceptable visual acuity with glasses or contact lens correction. Although graft preparation and surgical technique can be challenging, adaptation of technologies, such as femtosecond laser and intraoperative anterior segment optical coherence tomography, may help overcome these barriers to enable Bowman layer transplantation to become a more widely adopted procedure.
Summary:
Bowman layer transplantation may offer an alternative, less invasive treatment option for eyes with advanced, progressive keratoconus.
Related Concept Videos
Layers of the Epidermis
Stratum Basale
Stratum basale, also known as the stratum germinativum, is the deepest layer of the epidermis. It is composed of a single layer of actively dividing cells called basal cells or basal keratinocytes. These cells constantly undergo cell division to replenish the upper layers of the epidermis. Additionally, melanocytes, which...
Thematic Layering in GIS
Layers of the Heart Wall
The myocardium, the thickest layer, consists of cardiac muscle cells interconnected by intercalated discs and crisscrossing connective tissue fibers. These muscle fibers contract...
Boundary Layer Characteristics
Thin-Layer Chromatography (TLC): Overview
To begin the analysis, a mixture of compounds is spotted on the starting line on the TLC plate using a thin capillary. The bottom of the...
Layers of Connective Tissue Proper

