Fat Grafting in Managing Craniofacial Deformities
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Updated: Jan 25, 2026

Electroporation of Craniofacial Mesenchyme
Published on: November 28, 2011
Rafael Denadai1, Cesar Augusto Raposo-Amaral1, Cassio Eduardo Raposo-Amaral1
1From the Institute of Plastic and Craniofacial Surgery, SOBRAPAR Hospital.
Background:
The successful correction of craniofacial contour deformities remains a major challenge in plastic surgery. This article reviews important concepts and strategies for craniofacial fat grafting and presents a SOBRAPAR Hospital algorithm focused on achieving craniofacial contour symmetry as early as possible without compromising function.
Methods:
Principle-based methods (i.e., anatomical facial fat compartments, fluid accommodation model, multistage site-specific craniofacial fat grafting, and structural fat-grafting technique) were itemized into an algorithm to aid in planning and selecting the best surgical approach (i.e., bone and/or soft tissue procedures) in order to obtain craniofacial contour symmetry.
Results:
The treatment plan and choice of surgical technique implemented to address bone and/or or soft tissue deformities were determined by specific diagnosis, patient age at presentation, and functional status. Bony reconstruction in skeletally immature patients is reserved solely for those patients with functional issues.
Conclusion:
By adopting principle-based methods and fat compartment theory, we are able to achieve craniofacial contour symmetry and aesthetically pleasing outcomes without compromising function.
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