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Updated: Jan 25, 2026
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Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
Published on: February 17, 2023
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Device assisted enteroscopy in the elderly - A systematic review and meta-analysis
Stefania Chetcuti Zammit1, David S Sanders1, Reena Sidhu1
1Academic Department of Gastroenterology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals, Sheffield, UK.
Summary
Device assisted enteroscopy (DAE) shows higher diagnostic and therapeutic yields in elderly patients compared to younger ones. This procedure is safe for older adults, requiring less sedation and demonstrating comparable adverse event rates.
Area of Science:
- Gastroenterology
- Endoscopy
- Geriatric Medicine
Background:
- Device assisted enteroscopy (DAE) is increasingly utilized in elderly patients.
- Elderly patients present unique physiological challenges and comorbidities that complicate DAE procedures.
Purpose of the Study:
- To systematically evaluate the diagnostic and therapeutic yields of DAE in elderly patients.
- To compare the outcomes of DAE in elderly versus younger patient populations.
- To assess the safety and sedation requirements for DAE in the elderly.
Main Methods:
- A systematic literature search was conducted for studies involving elderly patients undergoing DAE.
- Pooled diagnostic yield (DY) and therapeutic yield (TY) were calculated.
- Outcomes including adverse events, length of small bowel examined, and sedation were compared between elderly and younger patients.
Main Results:
- Analysis included 14 articles with 3289 patients (1712 elderly). Meta-analysis of 9 studies (681 elderly, 1577 young) revealed higher DY and TY for DAE in elderly patients.
- Elderly patients demonstrated significantly better DY (1.83) and TY (2.28) compared to younger patients.
- No significant difference in major adverse events was observed between the groups, and elderly patients received less sedation.
Conclusions:
- DAE offers superior diagnostic and therapeutic yields in the elderly population.
- DAE is a safe and effective endoscopic procedure for elderly patients, requiring reduced sedation levels.
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