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Calcium intake improvement after nutritional intervention in paediatric patients with osteogenesis imperfecta

M B Zambrano1, T M Félix1,2, E D Mello1,3

  • 1Post Graduate Program in Child and Adolescent Health, University of Rio Grande do Sul, Porto Alegre, Brazil.

Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association
|May 1, 2019
PubMed

Insights

This study shows that a nutritional intervention significantly increased calcium intake in children with Osteogenesis Imperfecta (OI). This highlights the importance of nutritional therapy for improving bone health in OI patients.

Area of Science:

  • Pediatric Endocrinology
  • Nutritional Science
  • Bone Metabolism

Background:

  • Osteogenesis Imperfecta (OI) is a collagen disorder leading to bone fragility.
  • Standard OI treatment includes bisphosphonates.
  • Adequate calcium intake is crucial for managing bone disorders.

Purpose of the Study:

  • To assess the impact of a nutritional intervention (NI) on calcium intake and bone mineral density (BMD) in pediatric OI patients.
  • To evaluate the effectiveness of dietary changes in OI management.

Main Methods:

  • A non-randomized clinical trial involving 52 pediatric patients with OI.
  • Assessment of dietary calcium intake, anthropometry, and BMD at baseline and after 12 months.
  • Implementation of a food guidance program via mail.

Main Results:

  • Significant increases in total calcium intake (mg/day) and percentage of adequate calcium intake were observed post-NI.
  • A positive correlation was found between BMD variation and milk consumption in patients on bisphosphonate therapy.
  • Increased milk consumption was a notable outcome of the intervention.

Conclusions:

  • Nutritional intervention effectively increased calcium intake in pediatric OI patients.
  • Dietary management is a vital component of a multidisciplinary approach to OI treatment.
  • This study underscores the role of nutrition therapy in enhancing bone health outcomes for children with OI.
Abstract

Keywords:
bone healthbone mineral densitycalcium intakenutritionosteogenesis imperfectapaediatric

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