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Updated: Jan 25, 2026

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A GAP-GTPase-GDP-Pi Intermediate Crystal Structure Analyzed by DFT Shows GTP Hydrolysis Involves Serial Proton

Robert W Molt1,2, Erika Pellegrini3, Yi Jin4

  • 1Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, 46202, USA.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|May 1, 2019
PubMed

Keywords:
GTPaseNMR spectroscopyRhoA/RhoGAPcomputed proton statesphosphoryl transfer

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