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Related Concept Videos

Patient-centered Care01:13

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Patient-centered care involves delivering care beyond inpatient hospitalization. Reflective practice can enhance a patient-centered approach. Reflective practice is a process of reasoning that considers all aspects of the present situation, including practicalities, learning from personal practice, and consideration of patient needs. Patients appreciate care decisions made while considering their input. Involving the patient in their care provides the patient with a sense of contribution rather...
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Drug Dosing: Geriatric Patients01:15

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Drug Dosing: Obese Patients01:21

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In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

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In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
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Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

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Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
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ICER Can Do Better for Patients.

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This study highlights the financial disclosures of a key figure in allergy and asthma advocacy. It details funding sources for educational materials and patient research, emphasizing transparency in the field.

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Area of Science:

  • Medical Research
  • Public Health Advocacy

Background:

  • Disclosure of funding is crucial for transparency in medical research and patient advocacy.
  • The Asthma and Allergy Foundation of America (AAFA) receives significant funding from pharmaceutical companies for educational and research initiatives.

Purpose of the Study:

  • To outline the financial disclosures of the AAFA president and CEO.
  • To detail the sources of funding for AAFA's educational materials and patient research.

Main Methods:

  • Review of disclosed funding sources for the AAFA.
  • Identification of pharmaceutical companies providing grants to the AAFA.

Main Results:

  • The AAFA president and CEO has disclosed financial ties to multiple pharmaceutical companies.
  • Grants from companies including AstraZeneca, Genentech, GSK, Sanofi/Regeneron, and Teva contribute over 25% of AAFA's funding.

Conclusions:

  • Transparency in funding is essential for maintaining public trust in patient advocacy organizations.
  • Understanding funding streams is important for evaluating potential influences on research and educational content.