Capnocytophaga canimorsus Periprosthetic Joint Infection in an Immunocompetent Patient: A Case Report

Blane C Kelly1, David S Constantinescu1, William Foster1

  • 1Virginia Commonwealth University Health System, Richmond, VA, USA.

Abstract

Insights

A periprosthetic joint infection (PJI) caused by Capnocytophaga canimorsus, a bacteria from domestic pets, is rare in immunocompetent patients. This case highlights the need to consider this pathogen in PJI, even without immune compromise.

Area of Science:

  • Infectious Diseases
  • Orthopedic Surgery
  • Microbiology

Background:

  • Periprosthetic joint infection (PJI) is a serious complication after arthroplasty.
  • Common causative organisms are well-established, but unusual pathogens can occur.
  • Domestic pets can harbor bacteria capable of causing severe infections.

Purpose of the Study:

  • To report a case of PJI caused by Capnocytophaga canimorsus.
  • To review the literature on Capnocytophaga canimorsus as a cause of PJI.
  • To emphasize the importance of considering this pathogen in PJI diagnosis.

Main Methods:

  • Case report of an immunocompetent woman with a total hip arthroplasty.
  • Infection occurred after a domestic canine bite.
  • Diagnosis followed Musculoskeletal Infection Society criteria.
  • Treatment involved prosthesis explant, debridement, antibiotic spacer, and IV antibiotics.

Main Results:

  • The patient developed a periprosthetic hip infection due to Capnocytophaga canimorsus.
  • Despite treatment, the patient experienced a fatal myocardial infarction while awaiting prosthesis reimplantation.

Conclusions:

  • Capnocytophaga canimorsus is an uncommon cause of PJI, particularly in immunocompetent individuals.
  • This case underscores the necessity of considering Capnocytophaga canimorsus in PJI etiology, irrespective of the patient's immune status.
  • Prophylactic antibiotic treatment for canine bites and pre/postoperative patient counseling are recommended.

Related Concept Videos

Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
813
Structural Joints: Synovial Joints01:16

Structural Joints: Synovial Joints

Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...
6.5K
Data Reporting and Recording01:24

Data Reporting and Recording

Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.4K
Structural Joints: Fibrous Joints01:03

Structural Joints: Fibrous Joints

Fibrous joints are a type of joint where the bones are connected by fibrous connective tissue. These joints provide stability and minimal to no movement between the articulating bones. There are three types of fibrous joints.
Suture
All the bones of the skull, except for the mandible, are joined to each other by a fibrous joint called a suture. The fibrous connective tissue found at a suture strongly unites the adjacent skull bones and thus helps to protect the brain and form the face. In...
3.7K
Structural Joints: Cartilaginous Joints01:17

Structural Joints: Cartilaginous Joints

As the name indicates, at a cartilaginous joint, the adjacent bones are united by cartilage, a tough but flexible type of connective tissue. Unlike synovial joints, these types of joints lack a joint cavity and involve bones joined together by either hyaline cartilage or fibrocartilage.
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary...
4.0K
Joints01:26

Joints

Joints, also called articulations or articular surfaces, are points at which ligaments or other tissues connect adjacent bones. Joints permit movement and stability, and can be classified based on their structure or function.
Structural joint classifications are based on the material that makes up the joint as well as whether or not the joint contains a space between the bones. Joints are structurally classified as fibrous, cartilaginous, or synovial.
Fibrous Joints Are Immovable
The bones of a...
35.5K