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A left atrial appendage closure combined procedure review: Past, present, and future perspectives

Alessio Gasperetti1, Gaetano Fassini1, Fabrizio Tundo1

  • 1Heart Rhythm Center is the Department name; IRCCS, Centro Cardiologico Monzino is the name of the hospital, Milano, Italy.

Journal of Cardiovascular Electrophysiology
|May 2, 2019
PubMed

Insights

The combined procedure of left atrial appendage closure (LAAC) and atrial fibrillation (AF) ablation is a safe and effective stroke prevention strategy. Careful patient selection is key to maximizing benefits for nonvalvular AF patients.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Electrophysiology

Background:

  • Atrial fibrillation (AF) is a prevalent arrhythmia causing significant morbidity, particularly stroke.
  • Left atrial appendage closure (LAAC) offers an alternative to anticoagulation for stroke prevention in AF.
  • LAAC can be performed alone or combined with AF ablation.

Purpose of the Study:

  • To review and summarize the evidence supporting the combined procedure of LAAC and AF ablation.
  • To evaluate the safety and efficacy of this combined strategy.

Main Methods:

  • A comprehensive literature review of Medline-indexed studies on the combined procedure.
  • Analysis of data, aims, and scientific rationales from relevant publications.

Main Results:

  • Nine studies investigating the combined procedure were identified and analyzed.
  • The review synthesized data on the outcomes and rationale for the combined approach.

Conclusions:

  • The combined LAAC and AF ablation procedure is demonstrated to be safe and effective.
  • Optimizing patient selection is crucial for achieving the best outcomes with this combined strategy.
Abstract

Keywords:
atrial fibrillationcatheter ablationcombined ablationleft atrial appendageleft atrial appendage closurereviewstroke prevention

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