Related Experiment Video
Updated: Jan 25, 2026

Author Spotlight: Optimization of Ultrashort Peptide Matrices for Colorectal Cancer Organoids
Published on: May 3, 2024
Regularized differential evolution for a blind phase retrieval problem in ultrashort laser pulse characterization
D Gerth1, E Escoto2, G Steinmeyer2
1Faculty of Mathematics, Chemnitz University of Technology, Chemnitz 09107, Germany.
Abstract:
Obtaining the temporal shape of an ultrashort laser pulse using the method of dispersion scan entails solving a nonlinear inverse problem, a challenging prospect on its own, yet still aggravated when the pulse shape being measured is temporally varying from pulse to pulse. For this purpose, we use a Differential Evolution (DE) algorithm enhanced by three different regularization methods. The DE algorithm in its standard form is insufficient for reconstructing the pulse in the case of unstable pulse trains. By modifying it to retrieve two independent functions and with the help of regularization, we were able to show that it is possible to simultaneously infer the average length and the coherence length of the pulses. The latter is the shortest pulse the laser source can produce. We also discuss the three different approaches for regularization used in this paper, and from the numerical results we present, we can conclude that a spline-based regularization method is far superior compared to the two other methods under investigation.
Related Concept Videos
Blind Procedures
The Evidence for Evolution
Convergent Evolution
Blinding
Retrieval
Recall involves accessing information without cues, such as during an essay test, where individuals must retrieve facts and concepts from memory unaided. Another example is remembering the name of a colleague...
Phase Contrast and Differential Interference Contrast Microscopy
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...

