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Updated: Jan 25, 2026
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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
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Ischemic Diffusion Lesion Reversal After Endovascular Treatment
Joonsang Yoo1, Jin Wook Choi2, Seong-Joon Lee3
1From the Department of Neurology (J.Y., J.-H.H., S.-I.S.), Keimyung University School of Medicine, Daegu, Korea.
Stroke
|May 3, 2019
Summary
Complete reperfusion and shorter imaging times are key factors for diffusion-weighted imaging (DWI) lesion reversal after endovascular treatment (EVT) for acute ischemic stroke. This finding improves understanding of stroke recovery after EVT.
Area of Science:
- Neurology
- Radiology
- Interventional Cardiology
Background:
- Diffusion-weighted imaging (DWI) lesion reversal is observed after acute stroke reperfusion.
- Factors influencing DWI reversal post-endovascular treatment (EVT) require systematic investigation.
Purpose of the Study:
- To evaluate factors associated with DWI lesion reversal following EVT in acute ischemic stroke patients.
- To compare outcomes between patients with and without DWI reversal.
Main Methods:
- Retrospective analysis of 404 acute ischemic stroke patients undergoing EVT within 24 hours.
- Inclusion criteria: anterior circulation infarction, baseline and follow-up DWIs.
- DWI reversal defined as decreased DWI volume from baseline to follow-up.
Main Results:
- 15.5% of patients (63/404) demonstrated DWI reversal.
- Patients with DWI reversal showed significantly better 3-month functional outcomes (mRS 1 vs 2).
- Complete reperfusion (OR 1.954) and shorter time from baseline DWI to reperfusion (OR 0.991) were independently associated with DWI reversal.
Conclusions:
- Complete reperfusion is a significant predictor of DWI reversal.
- Shorter imaging-to-reperfusion time is independently associated with DWI reversal.
- These findings highlight critical factors for successful stroke treatment and recovery.
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