Related Experiment Video
Updated: Jan 25, 2026
Production of Haploid Zebrafish Embryos by In Vitro Fertilization
Published on: July 14, 2014
Factors associated with early in vitro fertilization treatment discontinuation
Bronwyn S Bedrick1, Kelsey Anderson1, Darcy E Broughton2
1Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Washington University School of Medicine, St. Louis, Missouri.
Objective:
To investigate factors associated with early IVF treatment discontinuation.
Design:
Retrospective cohort study.
Setting:
Academic medical center.
Patient(S):
Six hundred sixty-nine first-attempt IVF patients who did not have a live birth.
Intervention(S):
None.
Main Outcome Measure(S):
Treatment discontinuation and time to return for a second IVF cycle.
Result(S):
Women without IVF insurance coverage were more likely to discontinue treatment than women with insurance coverage (adjusted odds ratio [aOR] = 3.12; 95% confidence interval [CI], 2.22-4.40). African-American women were more likely to discontinue treatment (aOR = 2.95; 95% CI, 1.54-5.66) and returned for treatment more slowly (adjusted hazard ratio [aHR] = 0.44; 95% CI, 0.28-0.71) than non-Hispanic white women, regardless of IVF insurance coverage or income. Women with a poor prognosis were more likely to discontinue treatment than women with a good prognosis. Older women with IVF insurance coverage or a good prognosis had a shorter time to return for a second IVF cycle than older women without IVF insurance coverage or with a poor prognosis. Estimated income, distance to clinic, fertility diagnosis, number of oocytes retrieved, and history of previous live birth were not associated with treatment discontinuation or time to return for a second IVF cycle after adjustment for covariates.
Conclusion(S):
IVF insurance coverage, race, age, and future treatment prognosis are associated with IVF treatment discontinuation and time to return.
Related Concept Videos
01:24In Vitro Fertilization
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
01:38Fertilization
02:16Transcription Factors
04:01Factors Affecting Solubility
02:35Transcription Elongation Factors
The transcription elongation is regulated via pausing of RNA polymerase on several occasions during transcription. In bacteria, these halts are necessary because the transcription of DNA into mRNA is coupled to the translation of that mRNA...
01:19Factors Affecting Drug Distribution: Miscellaneous Factors
Age plays a significant role due to differences in body composition among different age groups. Infants, for instance, have a higher proportion of total body water and lower albumin levels, a protein that binds drugs in the bloodstream. This unique composition in infants enhances the...