Related Experiment Video
Updated: Jan 25, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Effects of Burdock tea on recurrence of colonic diverticulitis and diverticular bleeding: An open-labelled randomized
Akira Mizuki1, Masayuki Tatemichi2, Atsushi Nakazawa3
1Department of Internal Medicine, Keiyu Hospital, Yokohama, Japan. amizuki2@yahoo.co.jp.
Insights
Burdock tea effectively prevents acute colonic diverticulitis (ACD) recurrence. However, it did not show significant preventive effects on colonic diverticular bleeding (CDB) recurrence in this study.
Area of Science:
- Gastroenterology
- Clinical Nutrition
- Herbal Medicine
Background:
- Colonic diverticular bleeding (CDB) and acute colonic diverticulitis (ACD) have high recurrence rates.
- Preventing recurrence of CDB and ACD is a significant clinical concern for gastroenterologists.
Purpose of the Study:
- To evaluate the efficacy of burdock tea in preventing recurrences of CDB and ACD.
- To assess burdock tea as a potential preventative strategy for these conditions.
Main Methods:
- A randomized clinical trial involving patients newly diagnosed with CDB or ACD.
- Patients were assigned to either a burdock tea group (1.5g three times daily) or a control group.
- Recurrence rates and recurrence-free duration were monitored and compared between groups using Kaplan-Meier analysis and log-rank tests.
Main Results:
- Burdock tea significantly reduced ACD recurrence rates (10.6% vs. 31.8%) and increased recurrence-free duration (59.3 vs. 45.1 months).
- No significant preventive effect of burdock tea was observed for CDB recurrence.
- Statistical significance for ACD prevention was confirmed by log-rank test (p=0.012).
Conclusions:
- Daily intake of burdock tea is a potentially effective strategy for preventing acute colonic diverticulitis recurrence.
- Burdock tea does not appear to be effective in preventing colonic diverticular bleeding recurrence.
- Further research may explore mechanisms and optimal use of burdock tea in ACD management.
Abstract:
Colonic diverticular bleeding (CDB) and acute colonic diverticulitis (ACD) show high recurrence rates. The establishment of optimal strategies that prevent the recurrence of CDB and ACD is a major concern among gastroenterologists. This study aimed to assess the efficacy of burdock tea for preventing CDB and ACD recurrences. Newly diagnosed patients with CDB (n = 91) or ACD (n = 70) were randomly assigned into two groups. The experimental group received 1.5 g of burdock tea three times a day, whereas the control group did not receive any treatment. The median (interquartile range) of observation for recurrence of CDB or ACD was 22.0 (14.1) months and 30.3 (18.6), respectively. The burdock tea treatment showed significant preventive effects on recurrence of ACD. A lower ACD recurrence rate (5/47 [10.6%] vs. 14/44 [31.8%]) and longer recurrence-free duration was observed in the burdock tea group (59.3 months [95% CI: 54.0-64.7] vs. 45.1 months [95% CI: 37.1-53.0] by the Kaplan-Meier analysis; p = 0.012 by log rank test) than in the control group, although there was no significant preventive effects on the CDB recurrence. This randomized clinical trial demonstrated that daily intake of burdock tea could be an effective strategy for prevention of ACD recurrence, but not for CDB recurrence.
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