Integrating PROMIS® computerized adaptive tests into a web-based intervention for prostate cancer.

Area of Science:

• Oncology
• Psychology
• Health Technology

Background:

• Men with advanced prostate cancer (APC) undergoing hormone therapy often experience significant psychosocial distress.
• Existing interventions may not fully address the complex needs of this population.
• Technological adaptations in healthcare delivery are crucial for improving patient outcomes.

Purpose of the Study:

• To assess the feasibility of delivering PROMIS® computer adaptive tests (CATs) via a web-based platform.
• To evaluate the impact of a technologically adapted Cognitive-Behavioral Stress Management (CBSM) intervention on psychosocial functioning in men with APC.
• To examine the effectiveness of web-based interventions in managing distress during hormone therapy.

Main Methods:

• Randomized controlled trial with 192 men with APC undergoing hormone therapy.
• Intervention group received CBSM via video conference; control group received health promotion.
• PROMIS® CATs were administered weekly to assess anxiety, depression, fatigue, pain interference, and physical function.

Main Results:

• Moderate feasibility of repeated PROMIS® CAT administration via web-based method, with >50% completion rates.
• No significant group-by-time interactions for PROMIS® domains, but decreases in anxiety observed in both groups.
• Medical variables significantly related to psychosocial functioning over time.

Conclusions:

• Web-based PROMIS® CATs are feasible and beneficial for repeated assessment of psychosocial functioning.
• Web-based interventions show promise in reducing psychosocial distress and adverse symptoms in men with APC.
• This approach supports remote monitoring and management of psychosocial health in cancer patients.